The study is based on the experimental results for the seismic response of a pre-cast single storey RC industrial frame. The frame structure was tested in the European Laboratory for Structural Assessment (ELSA) of the Joint Research Centre (JRC) of the European Commission at Ispra, in the framework of the research project ‘Seismic behaviour of reinforced concrete industrial buildings’ of the Ecoleader programme. The primary objective of the project was to provide specific experimental evidence about the seismic behaviour of pre-cast single-storey frames for industrial buildings as compared to the corresponding cast-in-situ analogous structures. The results were expected to contribute to the correct calibration of Eurocode 8 design rules. Besides that, the experimental data have shown that under seismic excitations the curvatures below the top of the foundation exceed those above it. The interpretation of these data jointly with the data on cyclic tests of precast columns made it possible to gain more knowledge on the seismic behaviour of pre-cast column – foundation connection and assisted the development of design formulations.